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Blocking nuclear pore complex formation can help selectively kill cancer cells – News-Medical.net

Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that blocking the construction of nuclear pores complexes–large channels that control the flow of materials in and out of the cell nucleus–shrank aggressive tumors in mice while lea…

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Reviewed by Emily Henderson, B.Sc.Sep 28 2020
Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that blocking the construction of nuclear pores complexes–large channels that control the flow of materials in and out of the cell nucleus–shrank aggressive tumors in mice while leaving healthy cells unharmed.
The study, published in Cancer Discovery, a journal of the American Association for Cancer Research, reveals a new Achilles heel for cancer that may lead to better …

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U.K. Preparing COVID-19 Vaccine Trials That Deliberately Infect Study Subjects – NPR

Proponents say that such controversial “human challenge” studies can speed up vaccine development. But others cite ethical concerns.

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A syringe at the Royal Free Hospital, north London, shown as part of a vaccine trial.
Kirsty O’Connor – PA Images/PA Images via Getty Images
Researchers in Britain are preparing to start a controversial COVID-19 “human challenge” study in which dozens of healthy volunteers will be exposed to live coronavirus in an effort to speed up vaccine development.
The Human Challenge Programme will be conducted by Imperial College London, which said Tuesday in a statement that it would be working in coo…

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Can Placebos Work—Even When Patients Know They’re Fake? – WIRED

Researchers showed that a saline spray “treatment” reduced people’s emotional distress, even though the study subjects knew the spray wouldn’t do anything.

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For that reason, Tor Wager, a professor of neuroscience at Dartmouth College and a co-author of the study, says it will be important to track changes in the long run. We need to know something about which placebo effects last a long time, which ones fundamentally change something in your brain, he says. He suspects that different ingredientslike reinforcing belief in the effectiveness of the placebo at a particular timecould make placebos more or less durable. Ultimately, he says, the way to dis…

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A woman in her 30s died of coronavirus on a flight – BGR

A woman in her 30s died of coronavirus complications on a flight this summer. The woman received oxygen but ultimately died on the jetway. She suffered from und…

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  • A woman in her 30s died of coronavirus complications on a flight this summer.
  • The woman received oxygen but ultimately died on the jetway. She suffered from undisclosed high-risk health problems.
  • The COVID-19 patient died in late July, but her COVID-19 diagnosis was just announced.

The mortality rate of COVID-19 is low, and most people recover. That’s what statistics tell you. They also say that it’s people with preexisting conditions that are more likely to di…

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Can Placebos Work—Even When Patients Know They’re Fake? – WIRED
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A woman in her 30s died of coronavirus on a flight – BGR
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Coronavirus likely to become as ‘endemic’ as the flu and a vaccine might not be able to stop it, top UK scientist says – CNBC