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Clopidogrel, Not Aspirin, for Post-DAPT Monotherapy After PCI: HOST-EXAM – TCTMD

The Korean study will require replication in larger, more-diverse populations, and extended follow-up is welcome, experts say.



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Compared with aspirin monotherapy, maintenance therapy with clopidogrel beyond the initial dual antiplatelet (DAPT) period is associated with a reduction in death, MI, stroke, and other outcomes in patients who have had PCI, the HOST-EXAM study shows.
In the Korean cohort studied out to 24 months, the results were consistent across patient subgroups, regardless of baseline clinical and angiographic characteristics. The composite of all-cause death, MI, stroke, and BARC bleeding type 3 or greaterwithin…

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